A clinical study on nimesulide hepatotoxicity
نویسندگان
چکیده
منابع مشابه
Nimesulide-induced hepatotoxicity and fatal hepatic failure.
Non-steroidal anti-inflammatory drugs (NSAIDs) and cyclo-oxygenase-2 (cox-2) inhibitors are structurally heterogeneous drugs that share similar therapeutic actions and adverse effects. Hepatotoxicity, although a relatively rare adverse effect of this class of drugs, can be severe. This has led to the withdrawal of some NSAIDs from the market. Nimesulide is an NSAID, with cox-2 preference, which...
متن کاملCohort study of hepatotoxicity associated with nimesulide and other non-steroidal anti-inflammatory drugs.
OBJECTIVE To estimate the risk of acute hepatotoxicity associated with nimesulide compared with other non-steroidal anti-inflammatory drugs. DESIGN Retrospective cohort and nested case-control study. SETTING Umbria region, Italy. PARTICIPANTS 400 000 current, recent, and past users (almost 2 million prescriptions) of non-steroidal anti-inflammatory drugs between 1 January 1997 and 31 Dece...
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reinsurance is widely recognized as an important instrument in the capital management of an insurance company as well as its risk management tool. this thesis is intended to determine premium rates for different types of reinsurance policies. also, given the fact that the reinsurance coverage of every company depends upon its reserves, so different types of reserves and the method of their calc...
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ژورنال
عنوان ژورنال: International Journal of Research in Medical Sciences
سال: 2018
ISSN: 2320-6012,2320-6071
DOI: 10.18203/2320-6012.ijrms20184215